History of Angelman Syndrome

Dr. Harry Angelman, a pediatrician working in Warrington, Cheshire, first reported three children with this condition in 1965. It was initially presumed to be rare. In 1987, it was first noted that around half of the children with Angelman syndrome have a small piece of chromosome 15 missing chromosome 15q partial deletion. Since this time the condition has been reported more frequently and the incidence is now thought to be 1 in 25,000 children.