Controversy of P.A.N.D.A.S.

The PANDAS theory is only a hypothesis, and a highly controversial one, that has yet to be proven. It has engendered the use of controversial, dangerous and unproven treatment methodologies for children with tics and OCD, such as intravenous immunoglobulin (IVIG), plasma exchange, and the use of prophylactic antibiotics for the prevention of streptococcal infections. The Advisory Boards of the Tourette Syndrome Association do not currently recommend these procedures, and the NIH have also issued a warning about the use of these unproven methodologies.